【杂志介绍】
       《Therapeutic Drug Monitoring》是一本经同行评审的多学科期刊，主要面向药理学家、临床化学家、实验室人员、药剂师、药物研究人员和毒理学家人群。刊中收载特定类别药物的评论文章、原创文章、病例报告、技术说明和继续教育文章等。促进了临床药理学、病理学、毒理学和分析化学这些学科之间的知识信息交流。

April2023-Volume45-Issue1（2023年4月第45卷第1期）
https://journals.lww.com/drug-monitoring/toc/2023/02000

      纪念：查尔斯·皮彭格教授
      (In Memoriam: Professor Charles E. Pippenger)
      作者：Christians, Uwe MD, PhD

      Opinion Paper（述评）
      1. TDM生机勃勃!
      (TDM Is Alive and Kicking!)
      作者：Lemaitre, Florian PharmD, PhD; Hesselink, Dennis A. MD, PhD

      2. 合理设计的TDM临床试验:终点、陷阱和前景
      (The Appropriately Designed TDM Clinical Trial: Endpoints, Pitfalls, and Perspectives)
      作者：van Gelder, Teun MD, PhD

      3. 治疗药物监测中的新免疫分析：旅程走向何方？
      (New Immunoassays in Therapeutic Drug Monitoring: Where is the Journey Heading?)
      作者：Salamone, Salvatore J. PhD; Courtney, Jodi B. BS; Clarke, William A. PhD

      Short Communication（简报）
      1. 免疫抑制剂监测——第一种基于质谱的自动化临床分析仪级联的使用。
      (Immunosuppressant Monitoring—Performance of the First Mass Spectrometry–Based Automated Clinical Analyzer Cascadion).
      作者：Grote-Koska, Denis PhD; Czajkowski, Stefan Dipl-Ing; Staaden, Antje MSc; Brand, Korbinian MD

      Review Article（综述文章）
      1. 供体来源的游离DNA用于肾移植的个性化免疫抑制
      (Donor-Derived Cell-free DNA for Personalized Immunosuppression in Renal Transplantation)
      作者：Oellerich, Michael MD; Budde, Klemens MD; Osmanodja, Bilgin MD; Bornemann-Kolatzki, Kirsten PhD; Beck, Julia PhD; Schütz, Ekkehard MD; Walson, Philip D. MD

      2. 近40年来地高辛免疫测定法的显著改进：较新的测定法很少受干扰影响
      (Significant Improvement in Digoxin Immunoassays Over Four Decades: Newer Assays are Less Affected by Interferences)
      作者：Dasgupta, Amitava PhD

      3. 治疗药物监测在识别圣约翰草和处方药之间临床显著相互作用的效用
      (Utility of Therapeutic Drug Monitoring in Identifying Clinically Significant Interactions Between St. John's Wort and Prescription Drugs)
      作者：Steenkamp, Vanessa PhD; Parkar, Hafiza MSc; Dasgupta, Amitava PhD

      Original Article（原创文章）
      1. 四种β -内酰胺类抗生素非结合部分的可重复性定量:健康供者加标血浆的超滤与微透析比较
      (Reproducible Quantification of Unbound Fractions of Four Beta-Lactam Antibiotics: Ultrafiltration Versus Microdialysis of Spiked Healthy Donor Plasma)
      作者：Beijer, Gustaf MD; Clarin, Leona MS; Östervall, Jennie PhD; Barclay, Victoria PhD; Eliasson, Erik MD, PhD

      2. 多发性硬化症治疗期间模拟表位肽定量分析那他珠单抗的臂交换
      (Peptide Mimotope-Enabled Quantification of Natalizumab Arm Exchange During Multiple Sclerosis Treatment)
      作者：Page, Lesley J. PhD; Lagunas-Acosta, Jacqueline BSc; Heussen, Raphaela PhD; Castellana, Edward T. PhD; Messmer, Bradley T. PhD

      3. 免疫抑制剂微量取样测定飞行检查的结果
      (Results From a Proficiency Testing Pilot for Immunosuppressant Microsampling Assays)
      作者：Veenhof, Herman PharmD, PhD; Koster, Remco A. PhD; Junier, Lenneke A.T. BSc; Zweipfenning, Peter PharmD; Touw, Daan J. PharmD, PhD

      4. 手指微量取样法可替代静脉穿刺用于成人肾移植患者他克莫司、霉酚酸和泼尼松龙浓度的同步治疗性药物监测
      (Fingerprick Microsampling Methods Can Replace Venepuncture for Simultaneous Therapeutic Drug Monitoring of Tacrolimus, Mycophenolic Acid, and Prednisolone Concentrations in Adult Kidney Transplant Patients)
      作者：Scuderi, Carla MClinPharm; Parker, Suzanne PhD; Jacks, Margaret BNur; John, George T. MBBS; McWhinney, Brett PhD; Ungerer, Jacobus MBBS; Mallett, Andrew MBBS; Healy, Helen MBBS; Roberts, Jason PhD; Staatz, Christine PhD

      5. 高效和高灵敏度定量检测人血清和血浆中阿仑单抗的酶联免疫吸附测定法的开发和验证
      (Development and Validation of an Efficient and Highly Sensitive Enzyme-Linked Immunosorbent Assay for Alemtuzumab Quantification in Human Serum and Plasma)
      作者：Achini-Gutzwiller, Federica R. MD; Jol-van der Zijde, Cornelia M.; Jansen-Hoogendijk, Anja M.; Lankester, Arjan C. MD, PhD; Bredius, Robbert G. M. MD, PhD; van Tol, Maarten J. D. PhD; Moes, Dirk Jan A. R. PharmD, PhD; Schilham, Marco W. PhD

      6. 环孢素和他克莫司的药效学监测:健康志愿者活化t细胞调节基因表达的核因子的认识
      (Pharmacodynamic Monitoring of Ciclosporin and Tacrolimus: Insights From Nuclear Factor of Activated T-Cell–Regulated Gene Expression in Healthy Volunteers)
      作者：Djaelani, Yoana Aurelia MD; Giese, Thomas MD; Sommerer, Claudia MD; Czock, David MD

      7. 群体药代动力学模型对儿童实体器官移植受者他克莫司剂量需求的预测能力
      (Predictive Capacity of Population Pharmacokinetic Models for the Tacrolimus Dose Requirements of Pediatric Solid Organ Transplant Recipients)
      作者：Pasternak, Amy L. PharmD; Park, Jeong M. PharmD, MS; Pai, Manjunath P. PharmD

      8. 他克莫司的纵向暴露与肾移植患者新发糖尿病的关系
      (Longitudinal Exposure to Tacrolimus and New-Onset Diabetes Mellitus in Renal Transplant Patients)
      作者：Destere, Alexandre PharmD, ; Premaud, Aurélie PhD, PharmD; Monchaud, Caroline PhD, PharmD, Marquet, Pierre PhD, MD; Woillard, Jean-Baptiste PhD,PharmD

      9. 日本非小细胞肺癌患者纳武利尤单抗的群体药代动力学
      (Population Pharmacokinetics of Nivolumab in Japanese Patients with Nonsmall Cell Lung Cancer)
      作者：Tohi, Makiko MS; Irie, Kei PhD; Mizuno, Tomoyuki PhD; Okuyoshi, Hiroyuki BS; Hirabatake, Masaki MS; Ikesue, Hiroaki PhD; Muroi, Nobuyuki PhD; Eto,Masaaki MT; Fukushima, Shoji PhD; Tomii, Keisuke MD, PhD; Hashida, Tohru PhD

      10. ABCC2 1249G>A和- 24C>T多态性对中国维吾尔族癫痫患儿拉科酰胺疗效和血浆浓度的影响
      (Impact of ABCC2 1249G>A and −24C>T Polymorphisms on Lacosamide Efficacy and Plasma Concentrations in Uygur Pediatric Patients With Epilepsy in China)
      作者：Zhao, Ting MP; Li, Hong-jian MP; Zhang, Hui-lan MP; Feng, Jie MB; Yu, Jing MM; Wang, Ting-ting MP; Sun, Yan MM; Yu, Lu-hai MP