一、临床药理学与治疗学 (2023年第114卷第4期)

October 2023 - Volume 114 - Issue 4 (2023年10月第114卷第4期)
https://ascpt.onlinelibrary.wiley.com/toc/15326535/2023/114/4

Editorial（社论）
1. 为什么在氟嘧啶治疗前推荐DPYD（dihydropyrimidine dehydrogenase 二氢嘧啶脱氢酶）检测仍存在争议？
(Why is There Still Debate About Recommending DPYD-Testing Before Fluoropyrimidine Treatment?)
作者：Ingolf Cascorbi* (Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Germany)

Perspective（视角）
1. 定量系统药理学在儿科药物安全性评价中的应用
(Application of Quantitative Systems Pharmacology to Pediatric Drug Safety Assessment)
作者：Sherbet Samuels, Gilbert J. Burckart* (Office of Clinical Pharmacology, Center for Drug Evaluation and Research, FDA, USA)

White Paper（白皮书）
1. 真实世界数据和真实世界证据在药物开发和批准领域的临床药理学应用—一个行业视角
(Clinical Pharmacology Applications of Real-World Data and Real-World Evidence in Drug Development and Approval–An Industry Perspective)
作者：Rui Zhu* (Clinical Pharmacology, Genentech, Inc., USA)

Reviews（综述）
1. 对于FDA关于氟嘧啶化疗前DPYD检测决定的回应
(Response to the FDA Decision Regarding DPYD Testing Prior to Fluoropyrimidine Chemotherapy)
作者：Daniel L. Hertz* (Department of Clinical Pharmacy, University of Michigan College of Pharmacy, USA)
2. 阐明平衡核苷转运蛋白在药物发现和开发中的临床重要性
(Addressing the Clinical Importance of Equilibrative Nucleoside Transporters in Drug Discovery and Development)
作者：Raymond K. Hau, Nathan J. Cherrington* (Department of Pharmacology & Toxicology, College of Pharmacy, The University of Arizona, USA)
3. 欧洲监管决策中综合数据的案例
(A Case for Synthetic Data in Regulatory Decision-Making in Europe)
作者：Clara Alloza, Michael Batech* (Aetion, Inc., USA)
4. 可持续的分散临床试验的设计与实施
(Design and Execution of Sustainable Decentralized Clinical Trials)
作者：Pritibha Singh* (Novartis Pharma AG, Switzerland)

Research（研究）
1. 低疾病活动度的类风湿关节炎患者从托珠单抗到萨瑞鲁单抗的非药物转换：一项观察性研究
(Non-Medical Switching from Tocilizumab to Sarilumab in Rheumatoid Arthritis Patients with Low Disease Activity, an Observational Study)
作者：Nathan den Broeder* (Department of Rheumatology, Sint Maartenskliniek, The Netherlands)
2. 美国FDA在哨兵行动中上市后主动风险识别和分析系统的六年：对真实世界证据生成的启示
(Six Years of the US Food and Drug Administration's Postmarket Active Risk Identification and Analysis System in the Sentinel Initiative: Implications for Real World Evidence Generation)
作者：Judith C. Maro* (Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, USA)
3. 1997年至2018年美国妊娠前三个月患者的处方药使用模式
(Patterns of Prescription Medication Use during the First Trimester of Pregnancy in the United States, 1997–2018)
作者：Martha M. Werler* (Department of Epidemiology, Boston University School of Public Health, USA)
4. 急性粒细胞白血病患者口服阿扎胞苷的群体药代动力学及暴露-反应分析
(Population Pharmacokinetics of Oral Azacitidine, and Exposure–Response Analysis in Acute Myeloid Leukemia)
作者：Allison Gaudy* (Bristol Myers Squibb, USA)
5. 基于III期随机试验结果预测新药在临床实践中的治疗效果
(Predicting Treatment Effects of a New-to-Market Drug in Clinical Practice Based on Phase III Randomized Trial Results)
作者：HoJin Shin* (Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, USA)
6. 将人工智能工具重新用于疾病建模：神经退行性疾病中面部识别缺陷的案例研究
(Repurposing Artificial Intelligence Tools for Disease Modeling: Case Study of Face Recognition Deficits in Neurodegenerative Diseases)
作者：Gargi Singh, Murali Ramanathan* (Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, USA)
7. 不可切除肝细胞癌患者暴露于Tremelimumab后增殖性CD4和CD8 T细胞变化的建模
(Modeling of Proliferating CD4 and CD8 T-Cell Changes to Tremelimumab Exposure in Patients with Unresectable Hepatocellular Carcinoma)
作者：Xuyang Song* (AstraZeneca, Gaithersburg, USA)
8. 在肌萎缩性侧索硬化症中使用合并登记的混合对照临床试验：一项可行性研究
(Hybrid Controlled Clinical Trials Using Concurrent Registries in Amyotrophic Lateral Sclerosis: A Feasibility Study)
作者：Ruben P. A. van Eijk*, Ying Lu* (Department of Biomedical Data Science and Centre for Innovative Study Design, School of Medicine, Stanford University, USA)
9. 在开始使用甲氨蝶呤的类风湿关节炎患者大型队列中，甲氨蝶呤多谷氨酸暴露-反应模型
(Methotrexate Polyglutamates Exposure – Response Modeling in a Large Cohort of Rheumatoid Arthritis Patients Starting Methotrexate)
作者：Renske C. F. Hebing* (Amsterdam Rheumatology and Immunology Center, Amsterdam UMC Location Reade, The Netherlands)
10. 74种儿科抗癌药物的关键药代动力学参数为临床前研究提供帮助
(Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies)
作者：Nora Jamaladdin, Olaf Witt*, Till Milde* (Hopp Children's Cancer Center Heidelberg (KiTZ), Germany)
11. 克罗恩病患者在强制停止使用生物制品后的次优结局和再治疗率：一项基于全国人群的研究
(Suboptimal Outcomes and Retreatment Rate of Patients With Crohn's Disease After Forced Discontinuation of Biologics: A Nationwide Population-Based Study)
作者：Nai-Yu Chen, Ching-Lan Cheng* (Department of Pharmacy, Kaohsiung Veterans General Hospital, Taiwan; School of Pharmacy, Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Taiwan, China)
12.CYP2C19表型对Mavacamten暴露与由CYP诱导剂和抑制剂引起的药物相互作用的生理学药代动力学建模和模拟
(Physiologically Based Pharmacokinetic Modeling and Simulation of Mavacamten Exposure with Drug–Drug Interactions from CYP Inducers and Inhibitors by CYP2C19 Phenotype)
作者：Manting Chiang, Caroline Sychterz* (Bristol Myers Squibb, USA)

二、药理学评论
（本刊为双月刊，每两月更新一次，详见12月更新）

三、先进药物输送评论 (2023年第201卷)

October 2023 - Volume 201 (2023年10月第201卷)
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/201/suppl/C

Review article（综述文章）
1. siRNA疗法内在毒性和递送介导毒性的整体分析
(A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics)
作者：Sheyda Ranjbar, Xiuling Lu* (Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, USA)
2. 药物输送中的脉管系统器官趋向性
(Vasculature organotropism in drug delivery)
作者：Amruta A, Dalila Iannotta, Joy Wolfram* (School of Chemical Engineering, The University of Queensland, Australia)
3. 向单细胞封装发展的精密生物学和医学
(Towards single cell encapsulation for precision biology and medicine)
作者：Prerak Gupta, Jae-Won Shin* (Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, USA)
4. 介孔二氧化硅纳米颗粒的生物安全性研究；走向临床转化
(Biosafety of mesoporous silica nanoparticles; towards clinical translation)
作者：Araceli Lérida-Viso, Alba García-Fernández* (Unidad Mixta de Investigación en Nanomedicina y Sensores. Universitat Politècnica de València, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM) Universitat Politècnica de València, Universitat de València, Spain)
5. 长效微针制剂
(Long-acting microneedle formulations)
作者：Lalitkumar K. Vora, Ryan F. Donnelly* (School of Pharmacy, Queen's University Belfast, UK)
6. 使用荧光寿命成像显微镜（FLIM）探测类器官代谢：药物发现和疾病理解的下一个前沿
(Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding)
作者：Margarida Barroso, Ruslan I. Dmitriev* (Department of Molecular and Cellular Physiology, Albany Medical College, USA; Tissue Engineering and Biomaterials Group, Department of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Belgium)
7. RNAi疗法：扩大肝外疾病的应用并克服递送挑战
(RNAi therapies: Expanding applications for extrahepatic diseases and overcoming delivery challenges)
作者：Jong Won Lee, Yuhan Lee* (KU-KIST Graduate School of Converging Science and Technology, Korea University, Korea; Department of Anesthesiology, Perioperative, and Pain Medicine, Center for Accelerated Medical Innovation & Center for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, USA)
8. 用于治疗发展的3D环境中监测干细胞和类器官增殖的光谱技术
(Spectroscopic techniques for monitoring stem cell and organoid proliferation in 3D environments for therapeutic development)
作者：Wei Mao, Hyuk Sang Yoo* (Department of Biomedical Materials Engineering, Kangwon National University, Korea)
9. 胶体光子晶体在类器官研究中的应用
(Application of colloidal photonic crystals in study of organoids)
作者：Kai Huang, Zaozao Chen*, Zhongze Gu* (State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, China)
10. 眼表新生血管治疗的最新分子医学策略
(Up-to-date molecular medicine strategies for management of ocular surface neovascularization)
作者：Yunlong Yang* (Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, China)
11. 用于高级眼部药物递送的微针
(Microneedles for advanced ocular drug delivery)
作者：Katie Glover, Thakur Raghu Raj Singh* (School of Pharmacy, Queen’s University Belfast, Medical Biology Centre, UK)
12. 处理自身炎症性疾病和自身免疫性疾病中的TNF-α：从传统到生物制剂和基于RNA的纳米药物的前沿
(Tackling TNF-α in autoinflammatory disorders and autoimmune diseases: From conventional to cutting edge in biologics and RNA- based nanomedicines)
作者：Valentina Andretto, Giovanna Lollo* (Univ Lyon, Université Claude Bernard Lyon 1, France)
13. 血液-生物材料界面的功能再生
(Functional regeneration at the blood-biomaterial interface)
作者：Dina M. Ibrahim* (Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands)

四、药理学发展趋势 (2023年第44卷第10期)

October 2023 - Volume 44 - Issue 10 (2023年10月第44卷第10期)
https://www.cell.com/trends/pharmacological-sciences/issue?pii=S0165-6147(22)X0011-4

Spotlight（聚焦）
1. 使用一种常见配体揭示多巴胺受体分化
(Dopamine receptor divergence revealed using a common ligand)
作者：David R. Sibley*, Junwei Shi* (Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, USA)
2. 少有人走过的路：激活致癌激酶
(The road less traveled: activating an oncogenic kinase)
作者：Madhuri Paul, David A. Fruman* (Department of Molecular Biology and Biochemistry, University of California Irvine, USA)
Forum（论坛）
1. 基于试剂的表面受体寡聚化模型的验证
(Validation of agent-based models of surface receptor oligomerisation)
作者：Joanne C. Clark* (Institute of Cardiovascular Sciences, Level 1 IBR, College of Medical and Dental Sciences, University of Birmingham, UK)
2. 线粒体质量控制：抗病毒治疗的主要靶点？
(Mitochondrial quality control: prime targets for antiviral therapy?)
作者：Yijin Wang* (School of Medicine, Southern University of Science and Technology, China)

Opinion（意见）
1. 降钙素/PAC1受体剪接变异体：偏头痛研究的盲点
(Calcitonin/PAC1 receptor splice variants: a blind spot in migraine research)
作者：Tayla A. Rees* (School of Biological Sciences, University of Auckland, New Zealand)
2. 对迷幻剂致畸性的看法：斑马鱼模型的应用
(A perspective on psychedelic teratogenicity: the utility of zebrafish models)
作者：Omer A. Syed* (Department of Biology, University of Toronto Mississauga, Canada)

Reviews（综述）
1. 神经退行性疾病中细胞铁死亡的治疗抑制
(Therapeutic inhibition of ferroptosis in neurodegenerative disease)
作者：Sean K. Ryan, Timothy R. Hammond* (Sanofi, Rare and Neurologic Diseases, USA)
2. 生物节律促进情绪障碍的治疗
(Circadian biology to advance therapeutics for mood disorders)
作者：Apoorva Bhatnagar, Greg Murray* (Department of Biotechnology, Indian Institute of Technology Hyderabad, India; Centre for Mental Health, Swinburne University of Technology, Australia)
3. 肌肉萎缩：新的途径和潜在的药物靶点
(Muscle wasting: emerging pathways and potential drug targets)
作者：Aylin Domaniku, Serkan Kir* (Department of Molecular Biology and Genetics, Koc University, Turkey)
4. 猴痘病毒分支的致病性差异：对药物发现和疫苗开发的影响
(Differences in pathogenicity among the mpox virus clades: impact on drug discovery and vaccine development)
作者：Graciela Andrei* (Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Belgium)

Drug of the Month（本月最佳药物）
1. Trofinetide：Rett综合征的开创性治疗方法
(Trofinetide: a pioneering treatment for Rett syndrome)
作者：Harrison Parent, Colleen Niswender* (Department of Pharmacology, Vanderbilt University School of Medicine, USA)

五、药理学与治疗学 (2023年第250卷)

October 2023 - Volume 250 (2023年10月第250卷)
https://www.sciencedirect.com/journal/pharmacology-and-therapeutics/vol/250/suppl/C

Review article（综述文章）
1. 垂体瘤微环境的治疗靶向性
(Therapeutic targeting of the pituitary tumor microenvironment)
作者：Mirela-Diana Ilie, Gérald Raverot* (Inserm U1052, CNRS UMR5286, Cancer Research Center of Lyon, France)
2. DNA甲基化在免疫相关疾病个体化治疗中的作用
(The role of DNA methylation in personalized medicine for immune-related diseases)
作者：Manoj Kumar Gupta, Cheng-Jian Xu* (Centre for Individualised Infection Medicine (CiiM), a joint venture between the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH), Germany)
3. 超越他汀类药物：降低低密度脂蛋白和心血管事件的新药理靶点
(Beyond statins: New pharmacological targets to decrease LDL-cholesterol and cardiovascular events)
作者：Emanuel Raschi* (Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Italy)
4. 经导管主动脉瓣介入治疗后的抗血栓治疗
(Antithrombotic therapy following transcatheter aortic valve intervention)
作者：Harish Sharma, M. Adnan Nadir* (Department of Cardiology, Queen Elizabeth Hospital Birmingham, UK)
5. 聚焦超声介导的血脑/肿瘤屏障破坏用于胶质瘤治疗的抗癌药物递送：从实验室到临床
(Anticancer drug delivery by focused ultrasound-mediated blood-brain/tumor barrier disruption for glioma therapy: From benchside to bedside)
作者：Charlotte Bérard, Anthony Novell* (Aix Marseille Univ, APHM, CNRS, INP, Inst Neurophysiopathol, Hôpital Timone, Service Pharmacie, France; Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Frédéric Joliot, France)
6. 抗血管生成药物在血管异常治疗中的重新应用
(Repurposing of antiangiogenic agents for treatment of vascular anomalies)
作者：Julie Blatt* (Division of Hematology Oncology, Department of Pediatrics, and the Lineberger Clinical Cancer Center, University of North Carolina School of Medicine, USA)
7. 乳酸酸中毒和TGF-β同时补充导致缺氧癌症细胞在肿瘤微环境中的可塑性改变
(Lactate acidosis and simultaneous recruitment of TGF-β leads to alter plasticity of hypoxic cancer cells in tumor microenvironment)
作者：Saumya Rastogi, Subhadeep Roy* (School of Pharmaceutical & Population Health Informatics, DIT University, India; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, India)
8. 肿瘤微环境的潜在靶向以改善癌症病毒治疗
(Potential targeting of the tumor microenvironment to improve cancer virotherapy)
作者：Zi-Xian Liao, S. Ja Tseng* (Institute of Medical Science and Technology, National Sun Yat-sen University, Taiwan, China; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taiwan,  China)
9. 偏头痛的精准治疗：近期治疗进展和为了解异质性和治疗反应的潜在生物标志物
(Towards precision medicine in migraine: Recent therapeutic advances and potential biomarkers to understand heterogeneity and treatment response)
作者：Gabriella Juhasz* (Department of Pharmacodynamics, Faculty of Pharmaceutical Sciences, Semmelweis University, Hungary)
10. 肿瘤转移：分子机制和临床前景
(Cancer metastasis: Molecular mechanisms and clinical perspectives)
作者：Sameer Ullah Khan, Fayaz Malik* (The University of Texas MD Anderson Cancer Center, Division of Genitourinary Medical Oncology, Holcombe Blvd, USA; Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, India)
11. 髓母细胞瘤靶向治疗：从信号通路的异质性和当前的治疗困境到治疗策略的最新进展
(Medulloblastoma targeted therapy: From signaling pathways heterogeneity and current treatment dilemma to the recent advances in development of therapeutic strategies)
作者：Qiyue Wang, Ebrahim Mostafavi* (School of Pharmaceutical Science, Nanjing Tech University, China; Department of Medicine, Stanford University School of Medicine, USA)
12. 精蛋白对靶蛋白的降解：一种新兴的癌症治疗策略
(Target protein degradation by protacs: A budding cancer treatment strategy)
作者：Diksha Choudhary, Rajwinder Kaur* (Chitkara College of Pharmacy, Chitkara University, India)
13. 纤维增生性疾病中靶向成纤维细胞机械转导的新方法
(Novel approaches to target fibroblast mechanotransduction in fibroproliferative diseases)
作者：Maya Ezzo, Boris Hinz* (Keenan Research Institute for Biomedical Science of the St. Michael’s Hospital, and Faculty of Dentistry, University of Toronto, Canada)
14. 利用大数据和机器学习算法提取神经发育障碍的可能治疗靶点
(Use of big data and machine learning algorithms to extract possible treatment targets in neurodevelopmental disorders)
作者：Muhammad Ammar Malik, Jan Haavik* (Computational Biology Unit, Department of Informatics, University of Bergen, Norway; Department of Biomedicine, University of Bergen, Norway)
15. 乙二醛酶 I是预防代谢紊乱的新靶点
(Glyoxalase I is a novel target for the prevention of metabolic derangement)
作者：Edwin R. Miranda, Jacob M. Haus* (School of Kinesiology, University of Michigan, USA)

六、药物 (2023年第83卷第15期)

October 2023 - Volume 83 - Issue 15 (2023年10月第83卷第15期)
https://link.springer.com/journal/40265/volumes-and-issues/83-15

Current Opinion（现行意见）
1. 复发性多发性硬化症的升级与诱导/高效治疗策略：哪种最适合患者？
(Escalation Versus Induction/High-Efficacy Treatment Strategies for Relapsing Multiple Sclerosis: Which is Best for Patients?)
作者：Gilles Edan* (Empenn IRISA Research Group, INSERM Clinical Investigation Center, Pontchaillou University Hospital, France)

Review Article（综述文章）
1. PARP（poly ADP-ribose polymerase）抑制之外的卵巢癌治疗：当前和未来的选择
(Treatment of Ovarian Cancer Beyond PARP Inhibition: Current and Future Options)
作者：Vikas Garg, Amit M. Oza* (Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Canada)
2. 阿尔茨海默病：疾病修饰的新靶点和研究药物
(Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification)
作者：Jeffrey L. Cummings* (Department of Brain Health, Chambers-Grundy Center for Transformative Neuroscience, School of Integrated Health Sciences, University of Nevada Las Vegas (UNLV), USA)

Systematic Review（系统综述）
1. Dravet综合征的药物治疗：随机对照试验的系统评价和网络Meta分析
(Pharmacotherapy for Dravet Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials)
作者：Simona Lattanzi* (Department of Experimental and Clinical Medicine, Neurological Clinic, Marche Polytechnic University, Italy)

Adis Drug Evaluation（Adis药物评估）
1. Vutrisilan：一份遗传性转甲状腺素介导的淀粉样变性的多发性神经病综述
(Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis)
作者：Tina Nie* (Springer Nature, New Zealand)

AdisInsight Report（AdisInsight报告）
1.贝福替尼：首次获批
(Befotertinib: First Approval)
作者：Hannah A. Blair (Springer Nature, New Zealand)
2. Talquetamab：首次批准
(Talquetamab: First Approval)
作者：Susan J. Keam (Springer Nature, New Zealand)
3. Avacincaptad Pegol: ：首次批准
(Avacincaptad Pegol: : First Approval)
作者：Connie Kang (Springer Nature, New Zealand)

七、药理学研究 (2023年第196卷)

October 2023 - Volume 196 (2023年10月第196卷)
https://www.sciencedirect.com/journal/pharmacological-research/vol/196/suppl/C

Editorial（社论）
1. 2023年第19届世界基础与临床药理学大会免疫药理学会议
(Immunopharmacology sessions at the 19th World Congress of Basic & Clinical Pharmacology 2023)
作者：Hong Yong Peh, Pasquale Maffia* (Pulmonary and Critical Care Medicine Division, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, USA; School of Infection & Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK)

Review Articles（综述文章）
1. α2烟碱型乙酰胆碱受体，在与主细胞相关的抑制性中间神经元中具有独特和选择性表达的亚基
(The alpha2 nicotinic acetylcholine receptor, a subunit with unique and selective expression in inhibitory interneurons associated with principal cells)
作者：Markus M. Hilscher, Klas Kullander* (Department of Immunology, Genetics and Pathology, Uppsala University, Sweden)
2. 抗血管内皮生长因子联合糖皮质激素治疗与抗血管内皮生长因子单药治疗糖尿病黄斑水肿的比较，重点观察人工晶状体的药物注射次数和混杂因素：一项系统综述和Meta分析
(Anti-VEGF combined with ocular corticosteroids therapy versus anti-VEGF monotherapy for diabetic macular edema focusing on drugs injection times and confounding factors of pseudophakic eyes: A systematic review and meta-analysis)
作者：Chengming Chen, Xiaolong Yan* (Department of Ophthalmology, Tangdu Hospital, The Air Force Military Medical University, China; Department of Thoracic Surgery, Tangdu Hospital, The Air Force Military Medical University, China)
3. 长期抗逆转录病毒治疗成功的支柱
(Pillars of long-term antiretroviral therapy success)
作者：Lucia Taramasso* (IRCCS Ospedale Policlinico San Martino di Genova, Italy)
4. 阿克曼菌属：肿瘤治疗的潜在靶点和悬而未决的问题
(Akkermansia muciniphila: A potential target and pending issues for oncotherapy)
作者：Xu Zhao, Zhixu He* (Guizhou University Medical College, China; Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University, China)
5. 靶向TRPV1和TRPA1：天然草药对抗术后肠梗阻的可行策略
(Targeting TRPV1 and TRPA1: A feasible strategy for natural herbal medicines to combat postoperative ileus)
作者：Qi Liang, Chun-Jie Wu* (State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, China; Institute of Innovation, Chengdu University of Traditional Chinese Medicine, China)
6. 萝卜硫素：一种对抗糖尿病相关并发症的营养品
(Sulforaphane: A nutraceutical against diabetes-related complications)
作者：Sinenhlanhla X.H. Mthembu, Phiwayinkosi V. Dludla* (Biomedical Research and Innovation Platform, South African Medical Research Council, South Africa; Cochrane South Africa, South African Medical Research Council, South Africa)
7. 染色质因子：准备好作为转移性结直肠癌症的生物标志物了吗？
(Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?)
作者：Cristina Moreta-Moraleda, Sonia Forcales* (Immunology Unit, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Spain; Serra Húnter Programme, Immunology Unit, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Spain)
8. 大鼠强迫游泳试验演变的系统映射综述：方案和结果参数
(A systematic mapping review of the evolution of the rat Forced Swim Test: Protocols and outcome parameters)
作者：Christiane Brandwein* (Research Group Animal Models in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany)
9. 非酒精性脂肪性肝病(NAFLD)的天然产物：药物开发的新先导发现
(Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development)
作者：Lu Wang, Jinyong Peng* (School of Pharmacy, Anhui University of Chinese Medicine, China)
10. 一氧化氮/cGMP通路在心脏收缩和舒张中的调节：在心力衰竭治疗中的潜在作用
(Modulation of the nitric oxide/cGMP pathway in cardiac contraction and relaxation: Potential role in heart failure treatment)
作者：Rocco Mollace, Roberta Macrì* (Pharmacology Laboratory, Institute of Research for Food Safety and Health IRC-FSH, Department of Health Sciences, University Magna Graecia of Catanzaro, Italy)
11. 通过免疫原型和药物靶向增强个性化免疫检查点治疗
(Enhancing personalized immune checkpoint therapy by immune archetyping and pharmacological targeting)
作者：Claudia Cerella, Marc Diederich* (Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Fondation Recherche sur le Cancer et les Maladies du Sang, Luxembourg; Department of Pharmacy, College of Pharmacy, Seoul National University, Korea)
12. 营养品对超重或肥胖成年人体重的影响比较：111项随机临床试验的系统综述和网络Meta分析
(Comparative effects of nutraceuticals on body weight in adults with overweight or obesity: A systematic review and network meta-analysis of 111 randomized clinical trials)
作者：Hossein Shahinfar, Sakineh Shab-Bidar* (Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Iran; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Iran)
13. 胆汁酸代谢调节网络协调骨稳态
(Bile acid metabolism regulatory network orchestrates bone homeostasis)
作者：Tingwen Xiang, Ce Dou* (Department of Orthopedics, Southwest Hospital, Third Military Medical University (Army Medical University), China)
14. 硫化氢和磺胺或磺胺营养品：临床前和临床研究中的分类、差异和相关性
(Hydrogen sulfide and sulfaceutic or sulfanutraceutic agents: Classification, differences and relevance in preclinical and clinical studies)
作者：A. Martelli, V. Calderone* (Department of Pharmacy, University of Pisa, Italy)

Research article（研究文章）
1.DNA修复生物标志物指导PARP抑制剂联合化疗的使用：Meta分析和系统综述
(DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review)
作者：Zoe Phan, C. Elizabeth Caldon* (The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Australia)
2. 儿童炎症性肠病的双重生物治疗和小分子治疗
(Dual biological therapy and small molecules in pediatric inflammatory bowel disease)
作者：Francesca Penagini* (Department of Pediatrics, "Vittore Buzzi" Children’s Hospital, Italy)
3. 欧洲血脂异常治疗指南：新概念和未来挑战
(European guidelines for the treatment of dyslipidaemias: New concepts and future challenges)
作者：Angela Pirillo, Alberico L. Catapano* (Center for the Study of Atherosclerosis, E. Bassini Hospital, Italy; Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy)
4. 宿主ALDH2缺乏通过肠-肝轴加重非酒精性脂肪性肝炎
(Host ALDH2 deficiency aggravates nonalcoholic steatohepatitis through gut-liver axis)
作者：Zhan-Ming Li, Bing Han* (Center for traditional Chinese medicine and gut microbiota, Minhang Hospital, Fudan University, China)
5. ORAI1抑制剂对活化肥大细胞的稳定作用可抑制花生诱导的过敏反应和急性腹泻
(Stabilization of activated mast cells by ORAI1 inhibitor suppresses peanut-induced anaphylaxis and acute diarrhea)
作者：Gyeongseo Suk, Hae Woong Choi* (Division of Life Sciences, Korea University, Korea)
6. 微粒体谷胱甘肽转移酶1控制黑色素瘤的转移和治疗反应
(Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma)
作者：Jie Zhang* (Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, USA)
7. Tricin促进ATG-7依赖性α-突触核蛋白的自噬降解和多巴胺释放，以改善帕金森病的认知和运动缺陷
(Tricin promoted ATG-7 dependent autophagic degradation of α-synuclein and dopamine release for improving cognitive and motor deficits in Parkinson's disease)
作者：Xingxia Wang, Wei Hu, Liqun Qu, Betty Yuen Kwan Law* (Neher’s Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China)
8. CD22阻断调节小胶质细胞活性抑制脑出血后的神经炎症
(CD22 blockade modulates microglia activity to suppress neuroinflammation following intracerebral hemorrhage)
作者：Honglei Ren, Wenyan He* (Department of Neurology, Tianjin Neurological Institute, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Tianjin Medical University General Hospital, China; Advanced Innovation Center for Human Brain Protection, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, China)
9. 血浆细胞外囊泡长RNA预测非小细胞肺癌患者对新辅助免疫疗法的反应和生存率
(Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non‐small cell lung cancer)
作者：Wei Guo, Fang Lv* (Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China)
10. 基因工程副干酪乳杆菌可恢复结肠血管紧张素转换酶2 (ACE2)并减轻雌性ACE2敲除大鼠的高血压
(Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats)
作者：Xue Mei, Bina Joe* (Center for Hypertension and Precision Medicine, Department of Physiology and Pharmacology, College of Medicine and Life Sciences, University of Toledo, USA)
11. 富含槲皮素的鸟乳杆菌通过水解酶介导的嘌呤核苷降解来缓解高尿酸血症
(Quercetin-enriched Lactobacillus aviarius alleviates hyperuricemia by hydrolase-mediated degradation of purine nucleosides)
作者：Depeng Li, Yongfei Hu* (State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, China)
12. PIAS3通过TGF-β信号通路调节TXNIP促进肝细胞癌铁死亡
(PIAS3 promotes ferroptosis by regulating TXNIP via TGF-β signaling pathway in hepatocellular carcinoma)
作者：Wenfang Bao, Jialin Wang, Yong Gao* (Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, China)
13. 地塞米松通过调节肺免疫代谢来预防烟曲霉诱导的严重哮喘
(Dexamethasone protects against Aspergillus fumigatus-induced severe asthma via modulating pulmonary immunometabolism)
作者：Phyllis X.L. Gan, W.S. Fred Wong* (Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore)
14. 铁蛋白纳米偶联物诱导曲妥珠单抗脑递送促进小鼠HER2 +乳腺癌脑转移的抗肿瘤反应
(Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis)
作者：Marta Sevieri, Fabio Corsi* (Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Italy)
15. HDAC1抑制剂SAHA联合阿霉素治疗三阴性乳腺癌具有协同作用
(The combination of the HDAC1 inhibitor SAHA and doxorubicin has synergic efficacy in triple negative breast cancer in vivo)
作者：Yuheng Pang, Meisi Yan* (Department of Breast Surgery, Tumor Hospital of Harbin Medical University, China; Pathology Teaching and Research Section, Basic Medical College of Harbin Medical University, China)
16. 中成药治疗社区获得性肺炎指南
(Guideline on treating community-acquired pneumonia with Chinese patent medicines)
作者：Minghang Wang, Suyun Li* (The First Affiliated Hospital of Henan University of Chinese Medicine, China)
17. 包括PTT和2 ' 3 ' -cGAMP/CQ-LP在内的序列方案通过I型干扰素途径揭示了PTT的抗肿瘤免疫功能
(A sequential scheme including PTT and 2′3′-cGAMP/CQ-LP reveals the antitumor immune function of PTT through the type I interferon pathway)
作者：Xiaoshuang Song, Yu Zheng* (Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, China)
18. 雌激素缺乏通过肠道微生物群诱导骨质流失
(Estrogen deficiency induces bone loss through the gut microbiota)
作者：Zhiyuan Guan, Chunli Song* (Department of Orthopedics, Peking University Third Hospital, China)
19. piRNA-823是主动脉夹层新的潜在治疗靶点
(piRNA-823 is a novel potential therapeutic target in aortic dissection)
作者：Min Li, Tao Yu* (Clinical Laboratory, Central Laboratory, Qingdao Hiser Hospital Affiliated of Qingdao University (Qingdao Traditional Chinese Medicine Hospital), China)
20. 新型药物转运蛋白底物鉴定：一种基于代谢组学分析、计算机模拟配体筛选和生物验证的创新方法
(Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation)
作者：Anne T. Nies, Matthias Schwab* (Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany, and University of Tuebingen, Germany)
21. 靶向hnRNPC通过m6a修饰的ATF4抑制自身免疫性甲状腺疾病中甲状腺滤泡上皮细胞凋亡和程序性坏死
(Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease)
作者：Ke Mo, Hongmei Qu* (Key Laboratory of Spatiotemporal Single-Cell Technologies and Translational Medicine, Yantai Yuhuangding Hospital of Qingdao University, China; Departments of Obstetrics and Gynecology, Yantai Yuhuangding Hospital of Qingdao University, China)

八、抗病毒研究 (2023年第218卷)

October 2023 - Volume 218 (2023年10月第218卷)
https://www.sciencedirect.com/journal/antiviral-research/vol/218/suppl/C

Research article（研究文章）
1. 法匹拉韦和利巴韦林保护正常小鼠免受致死性CCHFV感染
(Favipiravir and Ribavirin protect immunocompetent mice from lethal CCHFV infection)
作者：Thomas Tipih, Heinz Feldmann* (Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, USA)
2. CUR-N399，是一种PI4KB抑制剂，用于治疗肠道病毒A71感染
(CUR-N399, a PI4KB inhibitor, for the treatment of Enterovirus A71 infection)
作者：Dorothy Hui Juan Cheong, Justin Jang Hann Chu* (Infectious Disease Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore)
3. 一种新型乙型肝炎病毒衣壳组装调节剂QL-007通过改变衣壳组装抑制HBV复制和感染
(A novel hepatitis B virus capsid assembly modulator QL-007 inhibits HBV replication and infection through altering capsid assembly)
作者：Jingyuan Xi, Zhe Cheng* (Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, China; Department of Nonclinical Development, Qilu Pharmaceutical Co, Ltd, China)
4. 桑霉素被SARS-CoV-2聚合酶优先并入病毒RNA中
(Sangivamycin is preferentially incorporated into viral RNA by the SARS-CoV-2 polymerase)
作者：Ryan P. Bennett,  Harold C. Smith* (OyaGen, Inc., USA)
5. 神经氨酸酶介导的甲型流感（H3N2）病毒血凝活性的新见解
(New insights into the neuraminidase-mediated hemagglutination activity of influenza A(H3N2) viruses)
作者：Rongyuan Gao, Larisa V. Gubareva* (Influenza Division, NCIRD, Centers for Disease Control and Prevention (CDC), USA)

Short communication（短通讯）
1. 猴痘VP39 2′-O甲基转移酶抑制剂能有效抑制猴痘病毒
(Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus)
作者：Michala Zgarbová, Evzen Boura* (Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Czech Republic)

九、英国药理学杂志 (2023年第180卷第19-20期)

（一）October 2023 - Volume 180 - Issue 19 (2023年10月第180卷第19期)
https://bpspubs.onlinelibrary.wiley.com/toc/14765381/2023/180/19

Review Article（综述文章）
1.组织蛋白酶与SARS-CoV-2感染：从致病因素到潜在治疗靶点
(Cathepsins and SARS-CoV-2 infection: From pathogenic factors to potential therapeutic targets)
作者：Shuxuan Zhao, Hong Qing*, Junjun Ni* (Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, China)

Research Article（研究文章）
1. 硫酸孕烯醇酮类似物差异调节GABAA受体关闭/脱敏状态
(Pregnenolone sulfate analogues differentially modulate GABAA receptor closed/desensitised states)
作者：Martin Mortensen, Bente Frølund* (Department of Neuroscience, Physiology and Pharmacology, University College London, UK; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark)
2. 用于治疗顽固性高血压的新一代可溶性鸟苷酸环化酶刺激剂BAY-747的鉴定和特征研究
(Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertension)
作者：Frank Wunder* (Lead Identification & Characterization, Pharma Research and Development Center, Bayer AG, Germany)
3. Comt–Dtnbp1基因相互作用引起的多巴胺能信号传导和行为改变及其临床相关性
(Dopaminergic signalling and behavioural alterations by Comt–Dtnbp1 genetic interaction and their clinical relevance)
作者：Francesca Managò, Francesco Papaleo* (Genetics of Cognition Laboratory, Neuroscience Area, Istituto Italiano di Tecnologia, Italy)
4. 射干苷激活Nrf2信号通路可防止颗粒物诱导的肺损伤中的铁死亡
(Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury)
作者：Tingting Dong, Liping Peng* (Department of Respiratory Medicine, The First Hospital of Jilin University, China)
5. BQ788揭示了神经胶质ET_B受体调节神经元胆碱能和氮能神经通路抑制肠道运动：与术后肠梗阻有关
(BQ788 reveals glial ET_B receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus)
作者：Elvio Mazzotta, Fedias L. Christofi* (Department of Anesthesiology, Wexner Medical Center, The Ohio State University, USA)
6. 大黄素通过核受体(Nur77)介导的谷氨酰胺酶1的表观遗传调控促进肝星状细胞衰老并减轻肝纤维化
(Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1)
作者：Li Chen, Shizhong Zheng* (Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, China)

（二）October 2023 - Volume 180 - Issue 20 (2023年10月第180卷第20期)
https://bpspubs.onlinelibrary.wiley.com/toc/14765381/2023/180/20

Commentary（评论）
1. 评论：外周神经损伤后跨性别和物种的保守转录编程预测神经性疼痛的治疗
(Commentary on: Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain)
作者：Joseph B. Lesnak, Theodore J. Price* (Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, USA)

Research Article（研究文章）
1. 小鼠创伤性脑损伤后采用普罗布考治疗可激活BDNF/TrkB通路，促进神经再生，改善脑功能缺陷
(Probucol treatment after traumatic brain injury activates BDNF/TrkB pathway, promotes neuroregeneration and ameliorates functional deficits in mice)
作者：Chen-Mei Chen, Shaw-Fang Yet* (Institute of Cellular and System Medicine, National Health Research Institutes, Taiwan)
2. EP2和EP4受体在恶性胶质瘤中的互补作用
(Complementary roles of EP2 and EP4 receptors in malignant glioma)
作者：Jiange Qiu, Qianqian Li* (Academy of Medical Science, Zhengzhou University, China; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, USA)
3. 复合物-42通过靶向ripk3介导的坏死减轻急性肾损伤
(Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis)
作者：Xiao-yan He, Ming-ming Liu* (Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-inflammatory of Immune Medicines, Ministry of Education, China)
4. 1型大麻素(CB1)受体的正变构调节剂(PAM)拮抗剂的动力学模型
(A kinetic model for positive allosteric modulator (PAM)-antagonists for the type 1 cannabinoid (CB1) receptor)
作者：Liang Yang, Xiao Zhu* (Beijing Friendship Hospital, Capital Medical University, China; Department of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, China)
5. 在K18-hACE2小鼠中，SARS-CoV-2感染的严重程度通过一种新型类固醇衍生物以性别特异性的方式减弱
(The severity of SARS-CoV-2 infection in K18-hACE2 mice is attenuated by a novel steroid-derivative in a gender-specific manner)
作者：Sachin A. Gupte* (Department of Pharmacology, New York Medical College, USA)

十、临床药代动力学 (2023年第62卷第10期)

October 2023 -Volume 62 - Issue 10 (2023年10月第62卷第10期)
https://link.springer.com/journal/40262/volumes-and-issues/62-10

Review Article（综述文章）
1. 肿瘤中激酶抑制剂的治疗药物监测
(Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology)
作者：Maud B. A. van der Kleij* (Division of Medical Oncology, Department of Clinical Pharmacology, The Netherlands Cancer Institute, The Netherlands)
2. FDA和EMA批准的丙型肝炎直接抗病毒药物介导的药代动力学药物相互作用的机制及其临床意义
(Mechanisms and Clinical Significance of Pharmacokinetic Drug Interactions Mediated by FDA and EMA-approved Hepatitis C Direct-Acting Antiviral Agents)
作者：Michael Murray* (School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Australia)
3. Imeglimin：临床药理学综述
(Imeglimin: A Clinical Pharmacology Review)
作者：Clémence Chevalier, Sébastien Bolze* (Poxel SA, France)

Original Research Article（原创研究文章）
1. 多格列艾汀在健康成人和2型糖尿病患者中的群体药代动力学分析
(Population Pharmacokinetic Analysis of Dorzagliatin in Healthy Subjects and Patients with Type 2 Diabetes Mellitus)
作者：Kun Wang, Fuxing Tang* (Shanghai Qiangshi Information Technology Co., Ltd., China; Hua Medicine (Shanghai) Limited, China)
2. 群体药代动力学分析支持阿片类药物使用障碍的初始治疗和从舌下给药丁丙诺啡到皮下给药丁丙诺啡缓释剂型（CAM2038）的桥接
(Population Pharmacokinetic Analysis Supports Initiation Treatment and Bridging from Sublingual Buprenorphine to Subcutaneous Administration of a Buprenorphine Depot (CAM2038) in the Treatment of Opioid Use Disorder)
作者：Marcus Björnsson, Fredrik Tiberg* (Pharmetheus AB, Sweden; Camurus AB, Sweden)
3. 多替拉韦群体药代动力学模型优化HIV-1感染婴儿、儿童和青少年的儿科给药剂量
(Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents)
作者：Hardik Chandasana* (Clinical Pharmacology, Modeling and Simulation, GSK, USA)
4. 伏立康唑的模型引导的精准用药：用真实世界的临床数据挑战已发表的伏立康唑非线性混合效应模型
(Towards Model-Informed Precision Dosing of Voriconazole: Challenging Published Voriconazole Nonlinear Mixed-Effects Models with Real-World Clinical Data)
作者：Franziska Kluwe, Charlotte Kloft* (Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Germany)
5. Mirikizumab在中度至重度活动性溃疡性结肠炎患者中的药代动力学：来自III期LUCENT研究的结果
(Mirikizumab Pharmacokinetics in Patients with Moderately to Severely Active Ulcerative Colitis: Results from Phase III LUCENT Studies)
作者：Laiyi Chua, Xin Cindy Zhang* (Global PK/PD and Pharmacometrics, Eli Lilly and Company, USA)
6. 促卵泡激素在卵巢刺激过程中的群体药代动力学分析：与体重、泌乳素及THADA和ADIPOQ基因多态性的关系
(Population Pharmacokinetic Analysis of Follicle-Stimulating Hormone During Ovarian Stimulation: Relation with Weight, Prolactin and Gene Polymorphism in THADA and ADIPOQ)
作者：Xiaowei Zhang* (NHC Key Laboratory of Reproductive Health and Medical Genetics, China Medical University, China)
7. Patisiran在肝移植后hATTR淀粉样变性和多发性神经病变患者中的药代动力学和药效学
(Pharmacokinetics and Pharmacodynamics of Patisiran in Patients with hATTR Amyloidosis and with Polyneuropathy After Liver Transplantation)
作者：Prajakta Badri* (Clinical Pharmacology and Pharmacometrics, Alnylam Pharmaceuticals, USA)