TCR-T细胞疗法
TCR (T cell receptor) -T细胞疗法 (T cell receptor-Therapy,TCR-T):是过继细胞疗法应用于肿瘤等疾病的一种新疗法,其利用T细胞的肿瘤杀伤特性,向T细胞中转入肿瘤特异性的TCR基因,并通过其表达的受体介导T细胞对肿瘤抗原的特异性识别,最终实现对肿瘤的裂解和杀伤效果。
参考文献
①《TCR T 细胞疗法的研究挑战和审评考虑》
http://chkdx-cnki-net-s.vpn.lib.zryhyy.com.cn:8118/kcms/detail/detail.aspx?QueryID=4&CurRec=3&dbcode=CHKJ&dbname=CHKJ1519&filename=SWZP202003024&urlid=&yx=&uid=WEEvREcwSlJHSldSdmVqM1BLY1pyb1JJalZwUDM3cWZDUlpuN0k1NFk3dz0=$9A4hF_YAuvQ5obgVAqNKPCYcEjKensW4IQM
②《TCR-T细胞疗法的开发与产业化》
http://chkdx-cnki-net-s.vpn.lib.zryhyy.com.cn:8118/kcms/detail/detail.aspx?QueryID=4&CurRec=1&dbcode=CHKJ&dbname=CHKJ2022&filename=ZXYZ202021005&urlid=&yx=&uid=WEEvREcwSlJHSldSdmVqM1BLY1pyb1JJalZwUDM3cWZDUlpuN0k1NFk3dz0=$9A4hF_YAuvQ5obgVAqNKPCYcEjKensW4IQM
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